Long-term effects of a Palaeolithic-type diet in obese postmenopausal women: a 2-year randomized trial

We report long-term effects in obese postmenopausal women of a Palaeolithic-type diet on anthropometric measurements and metabolic balance, in comparison with a diet according to the Nordic Nutrition Recommendations

C Mellberg; S Sandberg; M Ryberg; M Eriksson; S Brage; C Larsson; T Olsson; B Lindahl

2014

Key concepts

Scholarcy highlights

A Palaeolithic-type diet has greater beneficial effects versus an Nutrition Recommendations diet regarding fat mass, abdominal obesity and triglyceride levels in obese postmenopausal women; effects not fully sustained for anthropometric measurements at 24 months
Adherence to protein intake was poor in the PD group
Fat is redistributed from peripheral to central depots, which is associated with an increased incidence of diabetes and cardiovascular disease among postmenopausal women
We found that a diet with reduced carbohydrate and saturated fatty acid intake and a relative increase in the intake of protein, monounsaturated fats, and polyunsaturated fatty acids has strong and long-lasting effects on fat mass, body weight and abdominal obesity in postmenopausal women, but there were no significant differences in anthropometric measurements at 24 months between groups
Of interest is that we recently showed a 5-week PD to be associated with a 49% decrease in liver fat and increased insulin sensitivity linked to a 41% decrease in serum triglycerides
Palaeolithic-type diet Nordic nutrition recommendations visceral adipose tissue cardiovascular disease randomized clinical trial dual energy X-ray absorption nitrogen intake resting energy expenditure total energy expenditure physical activity energy expenditure generalized estimating equations total fat mass

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