Positional cloning of the mouse obese gene and its human homologue

The mechanisms that balance food intake and energy expenditure determine who will be obese and who will be lean

Yiying Zhang

2003

Scholarcy highlights

  • The mechanisms that balance food intake and energy expenditure determine who will be obese and who will be lean
  • The ob gene product may function as part of a signalling pathway from adipose tissue that acts to regulate the size of the body fat depot

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