Carbon Dots for Optical Imaging in Vivo

We report the first study of carbon dots for optical imaging in vivo

Sheng-Tao Yang

2009

Scholarcy highlights

  • There has been significant recent interest in the development of highly fluorescent nanomaterials as contrast agents for optical imaging in vivo. The imaging agents should ideally be bright, nontoxic, biocompatible, and stable against photobleaching
  • We report the first study of carbon dots for optical imaging in vivo
  • The results suggest that the carbon dots are brightly fluorescent in solution, as reported previously,9 and well-behaved as contrast agents in live mice
  • Upon the injection of a C-Dots solution or a CZnS-Dots solution, the mice were imagined in a Lumazone FA in vivo Imaging System with 470 nm excitation and 525 nm emission filters
  • The results reported here demonstrate that carbon dots, injected into mice via various ways, remain strongly fluorescent in vivo, which coupled with their biocompatibility and nontoxic characteristics might offer great potentials in optical imaging and related biomedical applications

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