Why is Chitosan Mucoadhesive?

We have examined the role of primary amino groups and the role of electrostatic attraction, hydrogen bonding, and hydrophobic effects on aggregation of gastric mucin in the presence of chitosan

Ioannis A. Sogias

2008

Scholarcy highlights

  • Chitosan is a biocompatible and biodegradable amino polysaccharide, which is soluble in aqueous solutions at pH < 6.5
  • We demonstrated that electrostatic attraction forces between chitosan and gastric mucin can be suppressed in the presence of 0.2 mol/L sodium chloride; this does not prevent the aggregation of mucin particles in the presence of this biopolymer
  • Electronic Supporting Information files are available without a subscription to ACS Web Editions
  • Files available from the ACS website may be downloaded for personal use only
  • Information about how to use the RightsLink permission system can be found at http://pubs.acs.org/page/copyright/permissions.html

Need more features? Save interactive summary cards to your Scholarcy Library.