Green Synthesis of Fluorescent Carbon Dots from Gynostemma for Bioimaging and Antioxidant in Zebrafish

Fluorescent carbon dots have been synthesized via the calcination method using natural gynostemma as the precursor, without any toxic ingredients or surface passivation chemicals

Xinjing Wei; Li Li; Jinlong Liu; Lidong Yu; Hongbin Li; Feng Cheng; Xiaotong Yi; Jinmei He; Bingsheng Li

2019

Scholarcy highlights

  • Fluorescent carbon dots have been synthesized via the calcination method using natural gynostemma as the precursor, without any toxic ingredients or surface passivation chemicals
  • The biotoxicity of CDs on the embryonic development of zebrafish is evaluated, the hatch rate and survival rate of embryos are around 90%, and the malformation rate is less than 10%
  • Because of the excellent fluorescence stability and biocompatibility, CDs can be used in zebrafish for bioimaging
  • The antioxidative stress property of CDs is investigated both in vitro and in vivo, and the presence of CDs can promote the mRNA expression of related genes to encode more antioxidant proteins in zebrafish
  • Fluorescent CDs would be a potential candidate for bioimaging and treating diseases caused by excessive oxidation damage, such as cancer, senility, and other diseases associated with aging
  • Such files may be downloaded by article for research use

Need more features? Save interactive summary cards to your Scholarcy Library.