Fluorimetric Detection of Candida albicans Using Cornstalk N-Carbon Quantum Dots Modified with Amphotericin B

Due to the advanced fluorescence property of N-carbon quantum dots, a new method to detect pathogenic fungi by newly synthesized cornstalk N-CQDs modified with water-soluble amphotericin B was developed

Dayu Yu; Ling Wang; Huanyu Zhou; Xiaojun Zhang; Lei Wang; Nan Qiao

2019

Key concepts

Scholarcy highlights

  • Due to the advanced fluorescence property of N-carbon quantum dots, a new method to detect pathogenic fungi by newly synthesized cornstalk N-CQDs modified with water-soluble amphotericin B was developed
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  • N-CQDs with blue fluorescence were initially synthesized according to a previous report and modified with amphotericin B on their surfaces
  • The high cost of water-soluble amphotericin B may hamper the large-scale application of the new detection method using alcohol-soluble amphotericin B was used in subsequent experiments, confirming its potential to broaden avenues for the detection of fungi
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