Cell-Permeable and Biocompatible Polymeric Nanoparticles for Apoptosis Imaging

We report for the first time cell-permeable and biocompatible polymeric nanoparticles consisting of a polymer conjugated to a near-infrared fluorescence -linked effector caspase-specific peptide

Kwangmeyung Kim; Misu Lee; Hyungkyu Park; Jong-Ho Kim; Sungwon Kim; Hesson Chung; Kuiwon Choi; In-San Kim; Baik L. Seong; Ick Chan Kwon

2006

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  • We report for the first time cell-permeable and biocompatible polymeric nanoparticles consisting of a polymer conjugated to a near-infrared fluorescence-linked effector caspase-specific peptide
  • The smart polymeric nanoparticle developed here is an attractive probe for real-time imaging of apoptosis in single cells
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