Continuous separation of nanoparticles by type via localized DC-dielectrophoresis using asymmetric nano-orifice in pressure-driven flow

This paper presents a nano-orifice based microfluidic device using a direct current dielectrophoresis method to continuously separate different types of micro and nanoparticles of similar sizes by their different electric conductivities in pressure-driven flow

Kai Zhao; Dongqing Li

2017

Scholarcy highlights

  • This paper presents a nano-orifice based microfluidic device using a direct current dielectrophoresis method to continuously separate different types of micro and nanoparticles of similar sizes by their different electric conductivities in pressure-driven flow
  • The DC-DEP force is generated by applying a low electric potential difference via a small nano-size orifice on one side wall of the channel and a micron size orifice on the opposite wall
  • Experiments were conducted by adjusting the electric conductivity of the suspending medium so that one kind of particles will experience positive DEP force while another experiences negative DEP
  • In comparison with the reported DC-DEP methods which are commonly used to separate microparticles by size and the alternative current DEP techniques which can separate different types of microparticles by applying high frequency alternating current with inserted microelectrodes, this method uses a pair of asymmetrical orifices on the opposite sides of channel walls to induce strong non-uniformity of electrical field and is capable of separating different kinds of nanoparticles
  • His research is in the area of electrokinetic-based microfluidics, nanofluidics and lab-on-a-chip technology
  • He has published over 290 papers in top international journals, 31 book chapters and 3 books

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