Effects of environmentally relevant concentrations of diclofenac in Mytilus trossulus

Diclofenac was completely excreted by mussels during the depuration phase

Klaudia Świacka; Katarzyna Smolarz; Jakub Maculewicz; Magda Caban

2020

Scholarcy highlights

  • Diclofenac was completely excreted by mussels during the depuration phase
  • Diclofenac caused an increase in the frequency of lesions in M. trossulus tissues
  • Awareness of the significance of this issue is increasing, many questions related to the ecotoxicology of pharmaceuticals remain unclear
  • Diclofenac is one of the drugs most commonly detected in the marine environment and its potential toxicity has been previously highlighted, its impact on organisms deserves a special attention
  • The study showed that mussels absorb diclofenac in their tissues and the highest recorded concentration was 1.692 μg/g dw on day 8
  • Applicability of histopathological techniques in ecotoxicology of drugs requires additional evaluation in future studies

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