Transcriptional control of the cell cycle

Cell division is a highly coordinated process

Barbara Berckmans; Lieven De Veylder

2009

Scholarcy highlights

  • Cell division is a highly coordinated process
  • Only a few transcriptional regulators are known, a significant amount of the genome is transcribed in a cell cycle phase-dependent manner
  • E2F–DP transcription factors and three repeat MYB proteins are responsible for the expression of genes at the G1-to-S and G2-to-M transition, respectively
  • Several new transcriptional regulators have been characterized, stressing the importance of transcriptional control during the cell cycle

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