Design and evaluation of bioenhanced oral tablets of Dunaliella salina microalgae for treatment of liver fibrosis

The results showed that all prepared tablets manifested uniform diameter and thickness

Farouk Kamel El-Baz

2020

Scholarcy highlights

  • The application of Dunaliella salina microalgae in nutraceutical products is limited due to poor aqueous solubility and low bioavailability of the existing β-carotene
  • The aim of the present study is the design of bioenhanced oral tablets of D. salina powder prepared by direct compression technique using the novel solubilizer, Sepitrap™ 80, and bioenhancers as bile salts
  • The results showed that all prepared tablets manifested uniform diameter and thickness
  • The eligibility of the prepared tablets was confirmed by the friability test
  • Further enhancement was observed after the addition of bile salts
  • Salina powder have a promising antifibrotic potential against TAA-induced fibrosis in rats

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