Hepatocyte resident afflictions continue to affect the human population unabated
2015
Key concepts
Scholarcy highlights
- Hepatocyte resident afflictions continue to affect the human population unabated
- The asialoglycoprotein receptor is primarily expressed on hepatocytes
- ligand-anchored nanocarriers provide an attractive option for asialoglycoprotein receptor targeted delivery
- The present review details various ligands and nanocarriers exploited for ASGPR mediated delivery of drugs
- Nanocarrier properties affecting ASGPR mediated uptake are discussed at length
- The review highlights the clinical relevance of ASGPR mediated targeting and applications in diagnostics
- Hepatocyte resident afflictions continue to affect the human population unabated. The asialoglycoprotein receptor is primarily expressed on hepatocytes and minimally on extra-hepatic cells
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