How accurately can subject-specific finite element models predict strains and strength of human femora? Investigation using full-field measurements

The results showed a high accuracy between predicted and measured principal strains

Lorenzo Grassi

2016

Scholarcy highlights

  • Fragility fractures due to osteoporosis are a huge problem in Western society
  • The aim of this study was to validate finite element models of human femora against experimental data from three cadaver femora, both in terms of femoral strength and of the full-field strain distribution collected with digital image correlation
  • Despite the low sample size and the single loading condition tested, the present combined numerical-experimental method showed that finite element models can predict femoral strength by providing a thorough description of the local bone mechanical response
  • The prediction accuracy is considerably high both for strains) and femoral strength<400 N,), finite element models have not yet been introduced in clinical practice
  • This study aimed to assess the ability of subject-specific FE models to predict principal strains and femoral strength in human femora
  • Strains were predicted with a high accuracy, comparable to the highest reported for human femora in analogous loading configurations)
  • A simple subject-specific finite element modelling technique, free from internal parameter calibration, accurately predicted the mechanical behaviour of human femora in a single-leg-stance configuration, both in terms of strain response and fracture load

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