MIND diet slows cognitive decline with aging

The study findings suggest that the MIND diet substantially slows cognitive decline with age

Martha Clare Morris; Christy C. Tangney; Yamin Wang; Frank M. Sacks; Lisa L. Barnes; David A. Bennett; Neelum T. Aggarwal


Scholarcy highlights

  • Dementia is the 6th leading cause of death in the U.S.1 and the prevention of cognitive decline, the hallmark feature of dementia, is a public health priority
  • We related the MIND diet score to cognitive decline in the Memory and Aging Project and compared the estimated effects to those of the Mediterranean and DASH diets, dietary patterns that we previously reported were protective against cognitive decline among the MAP study participants
  • In mixed models adjusted for age, sex, education, total energy intake APOEε4, smoking history, physical activity and participation in cognitive activities, the MIND diet score was positively and statistically significantly associated with slower rate of cognitive decline. Compared to the decline rate of participants in the lowest tertile of scores, the rate for participants in the highest tertile was substantially slower. The difference in rates was the equivalent of being 7.5 years younger in age
  • The MIND diet score was statistically significantly associated with each cognitive domain, for episodic memory, semantic memory and perceptual speed.
  • The correlation between the MIND score with cognitive change was statistically significantly higher compared with that for either the MedDiet or the DASH. In this community-based study of older persons, we investigated the relation of diet to change in cognitive function using an á priori-defined diet composition score based on the foods and nutrients shown to be protective for dementia
  • Strong associations of the MIND diet were observed with the global cognitive measure as well as with each of five cognitive domains
  • Concern that biased diet reporting could explain the findings is mitigated by the fact that statistical control for factors like obesity, education, age, and physical activity had no impact on the estimated MIND diet effect and the association remained strong in analyses that omitted the participants with MCI and whose diet scores changed over the study period

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