Label-free fluorimetric detection of CEA using carbon dots derived from tomato juice

A label-free assay for carcinoembryonic antigen and CEA-aptamer has been established based on this carbon dots

Hong Miao; Lan Wang; Yan Zhuo; Zinan Zhou; Xiaoming Yang

2016

Scholarcy highlights

  • A label-free assay for carcinoembryonic antigen and CEA-aptamer has been established based on this carbon dots
  • A facile-green strategy to synthesize carbon dots with a quantum yield of nearly 13.9% has been built up, while tomato juice served as the carbon source
  • A label-free sensitive assay for detecting carcinoembryonic antigen in a continuous and recyclable way has been proposed on the basis of adsorption and desorption of aptamers by the surface of CDs through a competitive mechanism
  • Thereby, quantitative evaluation of CEA concentration in a broad range from 1 ng mL−1 to 0.5 ng mL−1 with the detection limit of 0.3 ng mL−1 was realized in this way
  • This strategy can be applied in a recyclable way, broadening the sensing application of CDs with biocompatibility
  • The carbon dots were used for cell imaging, potentiating them towards diverse purposes

Need more features? Save interactive summary cards to your Scholarcy Library.