Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery

Alejandro Díaz-Moscoso


Homogeneous facial amphiphiles consisting in a cyclodextrin platform onto which a polycationic cluster and a multi-tail hydrophobic moiety have been installed self-organized in the presence of plasmid DNA to form nanometric complexes which exhibit broad-range transfection capabilities


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