Biomimetic bone-like composites fabricated through an automated alternate soaking process

Hydroxyapatite–gelatin composites have been proposed as suitable scaffolds for bone and dentin tissue regeneration

Daniel G.T. Strange

2011

Scholarcy highlights

  • Hydroxyapatite–gelatin composites have been proposed as suitable scaffolds for bone and dentin tissue regeneration
  • An existing process used to coat a surface with hydroxyapatite under near physiological conditions, the alternate soaking process, is modified and automated using an inexpensive “off the shelf” robotics kit
  • Samples were investigated by Fourier transform infrared spectroscopy, scanning electron microscopy, energy dispersive X-ray spectroscopy and nanoindentation
  • Calcium phosphate coatings formed by the alternate soaking process exhibited different calcium to phosphate ratios, with correspondingly distinct structural morphologies
  • Hydroxyapatite–gelatin composite coatings over 2 mm thick could be formed with little visible porosity
  • The hydroxyapatite–gelatin composites demonstrate a composition and mechanical properties similar to those of cortical bone

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