MEKKs, GCKs, MLKs, PAKs, TAKs, and Tpls: upstream regulators of the c-Jun amino-terminal kinases?

Regulation of the mitogen-activated protein kinase family members — which include the extracellular response kinases, p38/HOG1, and the c-Jun amino-terminal kinases — plays a central role in mediating the effects of diverse stimuli encompassing cytokines, hormones, growth factors and stresses such as osmotic imbalance, heat shock, inhibition of protein synthesis and irradiation

Gary R Fanger; Pär Gerwins; Christian Widmann; Matthew B Jarpe; Gary L Johnson

2002

Scholarcy highlights

  • Regulation of the mitogen-activated protein kinase family members — which include the extracellular response kinases, p38/HOG1, and the c-Jun amino-terminal kinases — plays a central role in mediating the effects of diverse stimuli encompassing cytokines, hormones, growth factors and stresses such as osmotic imbalance, heat shock, inhibition of protein synthesis and irradiation
  • Regulation of the JNK pathway provides an interesting example of how many different stimuli can converge into regulating pathways critical for the determination of cell fate

Need more features? Save interactive summary cards to your Scholarcy Library.