Impact of intravascular ultrasound guidance in stent deployment on 6-month restenosis rate: a multicenter, randomized study comparing two strategies—with and without intravascular ultrasound guidance

We aimed to investigate the impact of intravascular ultrasound -guided stent implantation on the 6-month restenosis rate, which has not yet been fully established in randomized trials

François Schiele; Nicolas Meneveau; Alain Vuillemenot; Da Dong Zhang; Sanjiv Gupta; Mariette Mercier; Nicolas Danchin; Bernard Bertrand; Jean-Pierre Bassand

2002

Scholarcy highlights

  • The 6-month angiographic restenosis rate was compared in patients with symptomatic ischemic heart disease who were randomly allocated to angioplasty and stent deployment, with versus without intravascular ultrasound guidance
  • We aimed to investigate the impact of intravascular ultrasound-guided stent implantation on the 6-month restenosis rate, which has not yet been fully established in randomized trials
  • No significant difference was observed in the minimal luminal diameter, but the stent lumen cross-sectional area was significantly larger in Group B
  • The difference in MLD was nonsignificant, whereas the lumen CSA was 20% larger in the IVUS-guided group
  • A nonsignificant 6.3% absolute reduction in the restenosis rate and a nonsignificant difference in MLD were observed in this study
  • We still cannot rule out a beneficial effect of IVUS guidance, this may have gone undetected owing to a lack of statistical power
  • A significant increase was observed in immediate and 6-month lumen size, as detected by intravascular ultrasound, indicating that ultrasound guidance in stent deployment may be beneficial

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