Measurement of true absorption, endogenous fecal excretion, urinary excretion, and retention of calcium in term infants by using a dual-tracer, stable-isotope method

A dual-tracer, stable-isotope method was used to measure the percentage of true calcium absorption, true calcium absorption rate, endogenous fecal calcium excretion rate, urinary calcium excretion rate, and calcium retention rate

Laura S. Hillman; Linda S. Johnson; Ding Z. Lee; Nancy E. Vieira; Alfred L. Yergey

2006

Scholarcy highlights

  • A dual-tracer, stable-isotope method was used to measure the percentage of true calcium absorption, true calcium absorption rate, endogenous fecal calcium excretion rate, urinary calcium excretion rate, and calcium retention rate
  • The α value was higher in infants receiving human milk or HMF than in those receiving EPF-20/750 formula or in previously reported infants fed standard formula; those given EPF-24/940 formula had intermediate values
  • In the crossover study, no significant differences were seen between formulas for α and for Va, Vf, or Vf per kilogram
  • Vu per kilogram was significantly decreased in infants receiving the higher mineral formula
  • Vf per kilogram was inversely related to birth weight
  • We conclude that increasing formula mineral content does not ensure increased retention; careful monitoring of individual infants remains indicated

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