Surface modification of chitosan films.

This study has demonstrated that it is conceivable to fine-tune surface properties which influence its response to bio-macromolecules by heterogeneous chemical modification

Varawut Tangpasuthadol

2003

Scholarcy highlights

  • The surface of chitosan films was modified using acid chloride and acid anhydrides
  • Chemical composition at the film surface was analyzed by attenuated total reflectance Fourier-transform infrared spectroscopy and X-ray photoelectron spectroscopy
  • ATR-FTIR data verified that the substitution took place at the amino groups of chitosan, forming amide linkages, and the modification proceeded to the depth at least 1 μm
  • Choices of molecules substituted at the amino groups of the glucosamine units did affect the hydrophobicity of the film surface, as indicated by air–water contact angle analysis
  • The improved surface hydrophobicity affected by the stearoyl groups promoted protein adsorption
  • This study has demonstrated that it is conceivable to fine-tune surface properties which influence its response to bio-macromolecules by heterogeneous chemical modification

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