Nanoparticle-based electrochemical DNA detection

Nanoscale architectures of DNA-linked particle networks are attractive for electrical detection of DNA hybridization

Joseph Wang

2003

Key concepts

Scholarcy highlights

  • Nanoscale architectures of DNA-linked particle networks are attractive for electrical detection of DNA hybridization
  • This article reviews a variety of new nanoparticle/polynucleotide assemblies for advanced electrical detection of DNA sequences
  • Recent activity has led to innovative and powerful nanoparticle-based electrochemical DNA hybridization assays based on a variety of detection schemes
  • Such protocols rely on the use of colloidal gold tags, semiconductor quantum dot tracers, polymeric carrier beads, or magnetic beads
  • Useful have been protocols based on capturing of metal nanoparticle tracers followed by dissolution and anodic-stripping voltammetric measurement of the metal tag
  • The use of nanoparticle tracers for designing multi-target electrochemical coding protocols will be documented

Need more features? Save interactive summary cards to your Scholarcy Library.