Re-evaluation of Evans Blue dye as a marker of albumin clearance in murine models of acute lung injury

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Jaideep Moitra

2007

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  • We have re-evaluated this technique with a specific focus of assessing the commonly used turbidity correction factors. These factors, originally developed and required in a spectrophotometric assay to quantify Evans Blue in human infant or dog serum, produced negative numbers when applied to murine models of acute lung injury
  • This factor may be of significant utility in animal models of inflammatory injury

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