Prediction of Pathological Stage is Inaccurate in Men with PSA Values above 20ng/mL

We examined 5193 consecutive patients subjected to radical prostatectomy for localized prostate cancer

Andrea Gallina

2006

Scholarcy highlights

  • We hypothesized that either very low or very high PSA values may limit the accuracy of pathological stage predictions
  • We examined 5193 consecutive patients subjected to radical prostatectomy for localized prostate cancer
  • For PSA ≤2.5 ng/mL, predictive accuracy was 76.7%, 72.3% and 82.8% for respectively ECE, SVI and LNI
  • Accurate staging of these patients may require alternative markers or staging schemes

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