Circulating thyroid hormone levels and iodothyronine deiodinase activities in Nile tilapia (Oreochromis niloticus) following dietary exposure to Endosulfan and Aroclor 1254

We evaluated the effects of two organochlorinated environmental contaminants, Endosulfan and Aroclor 1254 on peripheral thyroid hormone metabolism and thyroid hormone plasma levels in Nile tilapia

Ana Maria Coimbra; Maria Armanda Reis-Henriques; Veerle M. Darras

2005

Scholarcy highlights

  • We evaluated the effects of two organochlorinated environmental contaminants, Endosulfan and Aroclor 1254 on peripheral thyroid hormone metabolism and thyroid hormone plasma levels in Nile tilapia
  • Tilapia were exposed through diet to 0.1 and 0.5 μg g− 1 of Endosulfan and 0.5 μg g− 1 of Aroclor 1254 for 21 and 35 days
  • Decreased plasma T4 and rT3 levels were observed in tilapia exposed to the lower dose of Endosulfan, while treatment with a higher dose and Aroclor 1254 produced no changes
  • Plasma T3 levels were not affected by these compounds
  • It is concluded that dietary exposure of tilapia to Endosulfan or Aroclor 1254 can lead to changes in circulating thyroid hormone levels and/or in peripheral thyroid hormone metabolism
  • The changes in hormone metabolism differ between tissues, eventually reflecting tissue-specific differences in adaptation

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