Effects of teriparatide [rhPTH (1–34)] treatment on structural geometry of the proximal femur in elderly osteoporotic women

We evaluated effects of teriparatide injection on hip structure among a subset 558 postmenopausal women enrolled in the Fracture Prevention Trial

K UUSIRASI

2005

Scholarcy highlights

  • We evaluated effects of teriparatide injection on hip structure among a subset 558 postmenopausal women enrolled in the Fracture Prevention Trial
  • Teriparatide increased bone mass and improved bone geometric strength in both treatment groups compared to the placebo group, with the response being dose-related
  • Local cortical instability characterized by the buckling ratio decreased by 5.5% and 8.6% in the teriparatide 20 μg and TPTD40 groups, respectively, during the study period
  • These data were presented in part at the American Society for Bone and Mineral Research meeting held in Minneapolis, Minnesota on September 19–23, 2003

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