The clover and heart signs in vertebral scintigraphic images are highly specific of Paget's disease of bone

Bone scintigraphy used as a diagnostic technique frequently yields non-specific intense uptake by vertebrae

D Rotés-Sala

2003

Scholarcy highlights

  • Bone scintigraphy used as a diagnostic technique frequently yields non-specific intense uptake by vertebrae
  • The presence or absence of the clover or heart signs was determined in each scintigraphy
  • A specificity and sensitivity study was performed with the data obtained
  • Inter-radiologist concordance was almost perfect: Kappa 0.86
  • A study of concordance was made between two radiologists blinded to the real diagnosis
  • In cases with doubtful radiologic images, these findings on scintigraphic vertebral images may afford a definitive diagnosis of Paget’s disease of bone and obviate further confirmatory invasive diagnostic procedures

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