P-glycoprotein—A mediator of multidrug resistance in tumour cells

Regulation by phorbol ester and protein kinase-C inhibitors, and by a protein phosphatase inhibitor, of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant human-KB cells

U.A. Germann

2002

Scholarcy highlights

  • Regulation by phorbol ester and protein kinase-C inhibitors, and by a protein phosphatase inhibitor, of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant human-KB cells
  • Functional studies of P-glycoprotein in inside-out plasma membrane vesicles derived from murine erythroleukemia cells overexpressing MDR 3
  • Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein, P170: evidence for localization in brain capillaries and cross-reactivity of one antibody with a muscle protein

Need more features? Save interactive summary cards to your Scholarcy Library.