Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells

We have generated H-2b mice with a homozygous null mutation in the granzyme B gene

Jonathan W. Heusel; Robin L. Wesselschmidt; Sujan Shresta; John H. Russell; Timothy J. Ley

2004

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