This brief review provides a framework for discussing current approaches being used to determine the cellular localization and function of the high mobility group chromosomal proteins
2004
Scholarcy highlights
- This brief review provides a framework for discussing current approaches being used to determine the cellular localization and function of the high mobility group chromosomal proteins
- The evolutionary conservation in the primary and tertiary structure as well as the observed correlations between cell phenotype and quantitative changes in protein levels and in post-synthesis modifications suggests that these proteins are components obligatory for proper cellular function
- Proteins HMG 1, 2 are DNA-binding proteins which can distinguish between various types of single-stranded regions of the genome
- The data available presently suggests that these proteins are important structural elements of chromatin and chromosomes
Need more features? Save interactive summary cards to your Scholarcy Library.