Hyaluronidase activity and hyaluronate content of the developing chick embryo heart

Hyaluronidase activity and hyaluronate content were measured in the developing chick heart from embryonic day 3 through posthatching stages

Roslyn W. Orkin

2004

Scholarcy highlights

  • Hyaluronidase activity and hyaluronate content were measured in the developing chick heart from embryonic day 3 through posthatching stages
  • Hyaluronidase activity gradually declined to 63% of the initial level by embryonic day 16
  • The heart hyaluronidase is an endoglycosidase with an estimated molecular weight of 62,000, which degrades hyaluronate and, to a lesser extent, chondroitin sulfate at an acid pH optimum
  • Between embryonic days 5 and 12, the concentration of hyaluronate decreased to 25–30% of the initial level and remained constant thereafter
  • Dr Orkin is a Postdoctoral Fellow of the Arthritis Foundation and Dr Toole is an Established Investigator of the American Heart Association

Need more features? Save interactive summary cards to your Scholarcy Library.