Thyroid function in human pregnancy

A high incidence of mental retardation occurs in severe endemic goiter areas, but investigations have failed to relate development and retardation of children to maternal gestational hypothyroidism

Evelyn B. Man; Raymond H. Holden; Walter S. Jones

2016

Scholarcy highlights

  • A high incidence of mental retardation occurs in severe endemic goiter areas, but investigations have failed to relate development and retardation of children to maternal gestational hypothyroidism
  • On the Revised Stanford-Binet intelligence test in fine motor tests and in speech, children born to euthyroid women aged 15 to 17 and 35 to 43 years scored lower than progeny of 24-year-old women; children of hypothyroxinemic women taking inadequate thyroid replacement therapy scored lower than progeny of euthyroid or hypothyroxinemic women taking adequate thyroid therapy
  • ☆Supported in part by United States Public Health Service Research Grant AM-04890-01, -02 from the National Institute of Arthritis and Metabolic Diseases, which was transferred to HD-00415-03, -04, -05 from the National Institute of Child Health and Human Development; HD-01821-01, -02 from the National Institute of Child Health and Human Development; Contract PH-43-68-13 from the National Institute of Neurological Diseases and Stroke to the Child Study Center at Brown University; and by grants from the Warner-Lambert Research Institute
  • C. in October, 1968, and at the Biennial Meeting of the Society for Research in Child Development in Santa Monica, California, in March, 1969

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