Peroxiredoxin III protein expression is associated with platinum resistance in epithelial ovarian cancer

We investigated the association between peroxiredoxin III and chemotherapy resistance in ovarian cancer

Xin-yan Wang; Hai-jiao Wang; Xiu-qin Li

2013

Scholarcy highlights

  • We investigated the association between peroxiredoxin III and chemotherapy resistance in ovarian cancer
  • The two groups showed no significant differences in pathological classification and age, they differed significantly in tissue differentiation and stage
  • PRX III protein was significantly higher in the Pt-resistant serous carcinomas, in moderately and poorly differentiated, and in stage III and IV ovarian cancer tissues compared to the Pt-sensitive group
  • Peroxiredoxin III protein expression is associated with platinum resistance in epithelial ovarian cancer

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