Anti-Helicobacter pylori xanthones of Garcinia fusca

A new geranylated xanthone derivative, fuscaxanthone I, along with nine xanthones, a biphenyl and three biflavonoids were isolated from the roots of Garcinia fusca Pierre

Jannarin Nontakham

2013

Scholarcy highlights

  • A new geranylated xanthone derivative, fuscaxanthone I, along with nine xanthones, a biphenyl and three biflavonoids were isolated from the roots of Garcinia fusca Pierre
  • The isolated compounds were evaluated for antibacterial activity against Helicobacter pylori
  • Isojacareubin displayed the most potent activity against H. pylori HP40 clinical isolate with MIC 23.9 μM, which was approximately two times greater than that of the standard drug amoxicillin
  • Authors thank Mr Maurice Broughton, Chulabhorn Research Institute, Thailand, for proof reading the article

Need more features? Save interactive summary cards to your Scholarcy Library.