Association of IL-10 Gene Polymorphism (−819C > T, −592C > A and −1082G > A) with Preterm Birth

Five hundred and fifty nine women with term birth and 559 with preterm birth were recruited from Lucknow, India

Monika Pandey

2017

Scholarcy highlights

  • Five hundred and fifty nine women with term birth and 559 with preterm birth were recruited from Lucknow, India
  • Genetic association analysis was conducted between cases and controls
  • Subjects recruited as cases were women with singleton delivery before 37 wk of gestation and controls were with delivery after or on 37 wk
  • The genotyping was performed for rs1800871, rs1800872 and rs1800896 for assessing the allelic distribution, haplotypic association and linkage disequilibrium analysis
  • The IL-10 mRNA levels were significantly lower in cases

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