Water-soluble PEGylated silicon nanoparticles and their assembly into swellable nanoparticle aggregates

Water-soluble silicon nanoparticles were synthesized by grafting PEG polymers onto functionalized silicon nanoparticles with distal alkyne or azide moieties

Zejing Xu; Yejia Li; Boyu Zhang; Tapas Purkait; Alina Alb; Brian S. Mitchell; Scott M. Grayson; Mark J. Fink

2015

Scholarcy highlights

  • Water-soluble silicon nanoparticles were synthesized by grafting PEG polymers onto functionalized silicon nanoparticles with distal alkyne or azide moieties
  • The surface-functionalized silicon nanoparticles were produced in one step from the reactive high-energy ball milling of silicon wafers with a mixture of either 5-chloro-1-pentyne in 1-pentyne or 1,7 octadiyne in 1-hexyne to afford air and water-stable chloroalkyl or alkynyl-terminated nanoparticles, respectively
  • Linked Si nanoparticle clusters were synthesized via the CuAAC “click” reaction of functional Si NPs with α,ω-functional PEG polymers of various lengths
  • Dynamic light scattering studies show that the flexible globular nanoparticle aggregates undergo a solvent-dependent change in volume similar in behavior to hydrogel nanocomposites

Need more features? Save interactive summary cards to your Scholarcy Library.