Utilization of Chemically Synthesized Super Paramagnetic Iron Oxide Nanoparticles in Drug Delivery, Imaging and Heavy Metal Removal

In this study, Super Paramagnetic Iron Oxide Nanoparticles were produced by chemical co-precipitation method

P. Durga Sruthi

2018

Scholarcy highlights

  • In this study, Super Paramagnetic Iron Oxide Nanoparticles were produced by chemical co-precipitation method
  • The produced SPIONs were exploited for the production of core–shell SPIONs for drug delivery against bacteria and cancer cells, while the naked SPIONs were used as contrasting agent in X-ray imaging and for heavy metal removal
  • Core–shell SPIONs were prepared by a series of steps comprising the synthesis by chemical co-precipitation method, functionalized with a surfactant, followed by coating with drug—itraconazole and encapsulation with biopolymer
  • In-vitro drug release efficiency was assessed by antibacterial activity and anticancer activity
  • Synthesis and characterization of superparamagnetic iron oxide nanoparticles coated with silica.

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