Biocompatible bacterial cellulose membrane in dural defect repair of rat

Duraplasty is necessary in nearly 30% of all neurological surgeries

Frederico de Melo Tavares de Lima; Flávia Cristina Morone Pinto; Belmira Lara da Silveira Andrade-da-Costa; Jaiurte Gomes Martins da Silva; Olávio Campos Júnior; José Lamartine de Andrade Aguiar

2017

Scholarcy highlights

  • Duraplasty is necessary in nearly 30% of all neurological surgeries
  • Different tissues and materials have been evaluated in dura mater repair or as dural substitutes in neurosurgery
  • Forty adults males Wistar rats divided into two groups: a control and an experimental
  • The arachnoid underlying defect was disrupted with a narrow hook
  • There were no cases of infection, cerebrospinal fluid fistulae, delayed hemorrhages, behavior disturbances, seizures and palsies
  • The bacterial cellulose membrane showed to have suitable biocompatibility properties, was not induced immune reaction, nor chronic inflammatory response and absence of neurotoxicity signals

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