Integrated control of Boophilus microplus ticks in Cuba based on vaccination with the anti-tick vaccine Gavac TM

We have evaluated GavacTM in a large scale field trial wherein 588,573 dairy cattle were vaccinated with the aim to reduce the number of acaricidal treatments

Manuel Rodriguez Valle; Luis Mèndez; Mario Valdez; Miguel Redondo; Carlos Montero Espinosa; Milagro Vargas; Ricardo Lleonart Cruz; Humberto Perez Barrios; Guillermo Seoane; Emerio Serrano Ramirez; Oscar Boue; Jorge Lodos Vigil; Héctor Machado; Carlos Borroto Nordelo; Marisdania Joglar Piñeiro

2004

Scholarcy highlights

  • Boophilus microplus has developed resistance against a range of chemical acaricides which has stimulated the development of alternative methods such as vaccination against ticks
  • In Cuba, the Bm86-based recombinant vaccine GavacTM has been successfully used in a number of controlled laboratory and field trials in cattle against B. microplus
  • We have evaluated GavacTM in a large scale field trial wherein 588,573 dairy cattle were vaccinated with the aim to reduce the number of acaricidal treatments
  • Prior to the introduction of the vaccine, 54 clinical cases of babesiosis and six fatal cases were reported per 1000 animals
  • It was found that the number of acaricidal treatments could be reduced by 87% over a period of 8 years
  • The national consumption of acaricides in Cuba could be reduced by 82% after the implementation of the integrated anti-B. microplus control program
  • Fuente Particlede la Recombinant Vaccine for the Control of Cattle Tick Elfos Scientiae HavanaCuba 187–194

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