Headache associated with pituitary tumors

In this prospective designed study, we describe 64 consecutive patients presenting with primary pituitary masses at Neuroendocrinological Department of General Hospital of Fortaleza from October 2005 to December 2006

Jackson A. Gondim; João Paulo Cavalcante de Almeida; Lucas Alverne Freitas de Albuquerque; Michele Schops; Érika Gomes; Tânia Ferraz


Scholarcy highlights

  • Pituitary adenomas are basal midline tumors in the sella region, which are associated with headache in some patients
  • The most common types of tumor presented in the study were nonfunctioning adenomas, representing 46.9%, followed by prolactinomas, 18.8% and adrenocorticotrophic hormone producing adenomas, 17.2%
  • There was no association between familial history and presence of headache in our study group
  • We observed an anatomical importance of tumor size, optic chiasm compression, sellar destruction and cavernous sinus invasion in genesis of headache
  • The intrasellar pressure may be an important factor in the origin of pituitary headache
  • Further investigation studies must be done to clarify the relationship between ISP, pituitary tumor and headache

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