Imaging of Kaposi sarcoma

Kaposi sarcoma is a rare angioproliferative malignancy derived from the endothelium discovered by Hungarian dermatologist Moritz Kaposi in the late 1800s

Dhivya Addula; Chandan J. Das; Vikas Kundra

2021

Scholarcy highlights

  • Kaposi sarcoma is a rare angioproliferative malignancy derived from the endothelium discovered by Hungarian dermatologist Moritz Kaposi in the late 1800s
  • Human herpesvirus 8 is the primary cause of KS, but its incidence is influenced by genetics, the environment, and immunosuppression such as that experienced by patients with acquired immunodeficiency syndrome or immunosuppressive drugs
  • The incidence of KS has been decreasing because of the efficacy of highly active antiretroviral therapy for AIDS, KS is associated with patients that have had a solid organ transplant and are immunosuppressed and it is still prominent in Africa, partially due to the difficulty in accessing HAART
  • Imaging of abdominal Kaposi sarcoma Hepatic and splenic Kaposi sarcoma Hepatic KS is most commonly seen among patients with AIDS, with about 34% of cases diagnosed during autopsy ; it uncommonly presents during life
  • KS is no longer as prevalent as it once was due to the successful introduction of HAART for AIDS
  • Imaging using modalities such as CT, MRI, and PET/CT scans can aid in diagnosing, staging, and follow-up of KS

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