Properties and applications of undecylprodigiosin and other bacterial prodigiosins

This review describes recent advances in the production process, biosynthesis, properties, and applications of bacterial prodigiosins

Nada Stankovic

2014

Scholarcy highlights

  • The growing demand to fulfill the needs of present-day medicine in terms of novel effective molecules has lead to reexamining some of the old and known bacterial secondary metabolites
  • Production of prodigiosin in the most common producer strain Serratia marcescens has been described in great detail
  • This review describes recent advances in the production process, biosynthesis, properties, and applications of bacterial prodigiosins
  • Special emphasis is put on undecylprodigiosin which has generally been a less studied member of the prodigiosin family
  • It has been suggested that proteins involved in undecylprodigiosin synthesis, RedG and RedH, could be a useful addition to the biocatalytic toolbox being able to mediate regio- and stereoselective oxidative cyclization
  • Judging by the number of recent references, it has become clear that undecylprodigiosin and other bacterial prodigiosins still hold surprises in terms of valuable properties and applicative potential to medical and other industrial fields and that they still deserve continuing research curiosity

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