Ibuprofen Metabolism in the Liver and Gill of Rainbow Trout, Oncorhynchus mykiss

This study investigates the metabolism of ibuprofen by rainbow trout

C. F. Gomez; L. Constantine; M. Moen; A. Vaz; W. Wang; Duane B. Huggett

2011

Scholarcy highlights

  • The presence of pharmaceuticals in the environment has become an important topic of discussion with respect to pharmaceutical absorption, metabolism and elimination in fish
  • This study investigates the metabolism of ibuprofen by rainbow trout
  • In vitro metabolic loss of parent compound was measured in gill and liver S9 and microsomal fractions
  • Assays involving the induction and inhibition of specific CYP isozymes support CYP1A2 as a possible metabolic pathway in fish

Need more features? Save interactive summary cards to your Scholarcy Library.