Pharmacokinetics of co-trimoxazole and co-tetroxazine in geriatric patients

The resulting distribution volumes Vdβ and total plasma clearance values corresponded with the data obtained in young patients or volunteers

K. Naber

2005

Scholarcy highlights

  • The resulting distribution volumes Vdβ and total plasma clearance values corresponded with the data obtained in young patients or volunteers
  • In contrast to young volunteers, geriatric patients experienced a slight prolongation of renal excretion for both sulphonamides
  • In this group of patients the renal clearance was 2.42 ml/min for SMZ and 10.7 ml/min for SDZ

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