Autonomic cardiac abnormalities in alcohol-dependent patients admitted to a psychiatric department

The results indicated moderate parasympathetic alteration in alcohol-dependent patients treated in a psychiatric department

T. Rechlin; I. Orbes; M. Weis; W. P. Kaschka

2006

Scholarcy highlights

  • The patients showed a significantly increased heart rate, a significant reduction in the coefficient of variation while resting and a significant decrease of the high frequency power of spectral analysis compared with the normal subjects
  • Standardized heart rate analyses were performed in 60 drug-free patients with alcohol dependence, who were admitted consecutively to a psychiatric department, and in 60 healthy normal matched subjects
  • The investigations were carried out 3 weeks after admission and treatment on a closed ward to avoid autonomic hyperexcitability during withdrawal or relapse
  • The results indicated moderate parasympathetic alteration in alcohol-dependent patients treated in a psychiatric department
  • This may have implications for psychotherapeutic or psychopharmacological treatment strategies and prognosis in such patients with alcohol dependence

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