Mitochondrial distribution and inheritance

Mechanisms mediating the inheritance of mitochondria are poorly understood, but recent studies with the yeastsSaccharomyces cerevisiae andSchizosaccharomyces pombe have begun to identify components that facilitate this essential process

K. H. Berger; M. P. Yaffe

2005

Scholarcy highlights

  • Mechanisms mediating the inheritance of mitochondria are poorly understood, but recent studies with the yeastsSaccharomyces cerevisiae andSchizosaccharomyces pombe have begun to identify components that facilitate this essential process
  • These components have been identified through the analysis of conditional yeast mutants that display aberrant mitochondrial distribution at restrictive conditions
  • Some inheritance components and mechanisms appear to function in certain types of cells, other conserved proteins are likely to mediate mitochondrial behavior in all eukaryotic cells

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