Anti-V3 loop spectrotype in HIV-infected individuals during zidovudine therapy

Among the sera reactive in spectrotypic analysis, the percentage of those with p24 antigen positivity was significantly lower than those with no detectable p24 antigen. It could not be demonstrated by IEFRB that there was any effect of ZDV on the activity and the number of anti-V3 specific B-cell clones

R. Biselli; R. D'Amelio; V. Del Bono; A. Canessa; G. Mazzarello; D. Bassetti; M. Anselmo

2005

Scholarcy highlights

  • Among the sera reactive in spectrotypic analysis, the percentage of those with p24 antigen positivity was significantly lower than those with no detectable p24 antigen. It could not be demonstrated by IEFRB that there was any effect of ZDV on the activity and the number of anti-V3 specific B-cell clones
  • Spectrotype of anti-gp120 antibodies remains stable during the course of human immunodeficiency virus disease
  • R., D'Amelio, R., Del Bono, V. et al Anti-V3 loop spectrotype in human immunodeficiency virus-infected individuals during zidovudine therapy

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