History of N-Acetylcysteine

N-Acetylcysteine, commonly referred to as NAC, is the N-acetylated form of the amino acid cysteine. It is rapidly deacetylated during first-pass metabolism to the essential amino acid cysteine and stored by the liver, which uses and releases it as needed

Leonore A. Herzenberg

2018

Scholarcy highlights

  • N-Acetylcysteine, commonly referred to as NAC, is the N-acetylated form of the amino acid cysteine. It is rapidly deacetylated during first-pass metabolism to the essential amino acid cysteine and stored by the liver, which uses and releases it as needed
  • It is stored, utilized, and/or released into the bloodstream as glutathione, a cysteine-containing tripeptide that serves as a detoxifying agent, a coenzyme for multiple enzymes, and a key component of the electron transport system
  • These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves
  • Other groups conducting studies discussed in this volume have worked, I believe, with other NAC sources
  • Neither we nor BioAdvantex have secured FDA approval for any clinical uses

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