Nanoparticles: Cellular Uptake and Cytotoxicity

Understanding the interactions of nanoparticles with cells and how these interactions influence their cellular uptake is essential to exploring the biomedical applications of NPs, for drug delivery

Isaac M. Adjei

2014

Scholarcy highlights

  • Understanding the interactions of nanoparticles with cells and how these interactions influence their cellular uptake is essential to exploring the biomedical applications of NPs, for drug delivery
  • A crucial consideration is whether such interactions might cause any toxicity, starting with how NPs interact in transit with the biological environment prior to their interactions with targeted cells and tissues
  • Understanding the effects of various NP characteristics on cellular and biological processes could help in designing NPs that are efficient and nontoxic
  • Panyam J, Labhasetwar V Dynamics of endocytosis and exocytosis of poly(D, L-lactide-co-glycolide) nanoparticles in vascular smooth muscle cells

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