Effects on Pharmaceuticals in the Environment — an Overview and Principle Considerations

Due to a lack of concern regarding the occurrence and effects of pharmaceuticals in the environment, no data appears in the literature until the middle of the 1970S

P. Pfluger; D. R. Dietrich

2013

Scholarcy highlights

  • Due to a lack of concern regarding the occurrence and effects of pharmaceuticals in the environment, no data appears in the literature until the middle of the 1970S
  • Environmental Effects of Pharmaceuticals on Organisms and Ecosystems the calculation of retention in the sewage treatment plants would provide a better basis for environmental risk assessment
  • Of the pharmaceuticals which predominate in the analyses of environmental samples as well as the lists compiled from prescription data, most belong to the class of analgesics, antibiotics, hypotensives, antiasthmatics, diuretics and psycholeptics
  • As mammalian metabolism of the parent compound and excretion as well as the biodegradability of the parent compound or its primary metabolites are compound specific, tlre sewage treatment plant retention and environmental fate of pharmaceuticals has be to investigated on a case-by-case basis, as outlined in the recent review by Ayscough et al
  • Specific tests, tailored to include the compound-specific mode of action of a given pharmaceutical, have to be carried out to provide a better basis for emironmental risk assessment

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